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Basic nutritional support such as a multivitamin, vitamin D, omega-3 fatty acids, adequate protein intake, and balanced electrolytes is usually well tolerated and may help maintain overall health during weight loss

Serotonin, as well-known as 5-hydroxytryptamine (5-HT), a small monoamine molecule primarily known as a neurotransmitter, is involved in the regulation of various physiologic procedures including cognition, mood, aggression, mating, feeding and sleep 12

NDA submission The NDA package will include all preclinical data, Phase 1, 2, and 3 trial results, manufacturing information, proposed labeling, and risk management plans

This approach aimed to minimise bias from using Ang-II inhibiting AHMs as the reference group, ensuring that key findings were not obscured

The trial will employ a randomized, double-blind, parallel-group design

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