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In contrast, SMAX1 (full-length or D2) showed no significant HDX changes upon complex formation, consistent with a transient and dynamic mode of interaction (Supplementary Fig

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As overuse of the wrist muscles is considered the most likely cause on average, it makes sense that symptoms may remain as long as the wrist is overused

avoidance of saunas, hot tubs, and tight underwear, all of which can reduce sperm quantity and quality, are also recommended