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Serial dilutions of dihexa in 50% DMSO or water were prepared from the stock used to dose the animals to be used for preparation of a standard curve
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These approaches typically involve: Lower maintenance doses (200-300mcg daily) Monthly assessment checkpoints Flexible adjustment windows Extended rest periods (4-6 weeks minimum) Research Note: Extended protocols should only be undertaken with comprehensive monitoring and documentation
Reed JW
& Gonzalez, A
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