Glutathione ( 3a ) also reacts with organic electrophiles ( R ), such as several reactive metabolites of environmental contaminants and pharmaceutical drugs, and with metal ions of thiophilic elements ( M ) to yield the corresponding glutathione thioethers ( 5a ), alkyl-cysteines ( 5b ) and mercapturic acids ( 5c )
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
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doi: 10.1080/19490976.2020.1826761 34