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Researchers at the University of Alberta conducted a study with lab mice showing that the use of Ozempic may shrink the size of the heart muscle

Secondly, GLP-1RAs attenuate apoptosis induced by TNF- by ameliorating mitochondrial dysfunction related to activating the GLP-1R/cAMP/PKA and AMPK/SIRT1 pathway [94, 157, 158]

ADA guidance also notes benefits of GLP-1 RAs in diabetes patients who also have cardiovascular disease, chronic kidney disease, or obesity-linked complications