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Applying the modified Response Evaluation Criteria in Solid Tumors (mRECIST), we observed that patients with higher intracellular GSH levels responded worse to neoadjuvant chemotherapy, as indicated by MRI scans, than those with lower intracellular GSH levels (Fig

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Figure 4 To further measure cell death upon treatment with MitoQ, DPI and vincristine, we measured caspase 3/7 activation using Caspase-Glo 3/7 (Promega) ( Figure 4D )