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External factors such as nutrition, stress, and exposure to toxins can influence the epigenetic marks on the igf-2 gene

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In this section, we will focus on how these programs contribute to both normal physiology and disease

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Notably, LEO activates the METTL3/AKT1S1 axis to induce autophagy, ameliorating macrophage lipid accumulation and suppressing atherosclerotic plaque formation (Yu et al., 2024)

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