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However, this heightened activity can also increase gastrointestinal side effects during the first few weeks, making a careful transition and dose escalation especially important for patient comfort and persistence

In 4 trials dapagliflozin was used as monotherapy, and in 8 trials dapagliflozin was used as add-on to background antidiabetic therapy or as combination therapy with metformin HCl [see Clinical Studies ]

So, let's pull back the curtain on Aetna's policies, what drives their decisions, and what your actual options are

Vitamin B 12. BMJ, vol

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Before anything else