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Contraindications ORLISTAT is contraindicated in: Pregnancy [see Use in Specific Populations (8.1)] Patients with chronic malabsorption syndrome Patients with cholestasis Patients with known hypersensitivity to ORLISTAT or to any component of this product 5

If the circulating B12 exceeds the binding capacity of the blood, the excess is excreted in the urine

[1] [15] Your doctor may recommend monitoring your thyroid function tests after starting or changing your Rybelsus dose

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Best for: Occasional constipation while on a GLP-1 Bloating after meals Digestive discomfort Gut bacteria support Daily regularity Semaglutide and tirzepatide users Start your journey Feel more comfortable on your GLP-1 routine with GLP-1 Support Built for people taking semaglutide or tirzepatide Supports gentle regularity without stimulant laxatives Helps reduce occasional bloating and digestive discomfort Includes Akkermansia muciniphila for gut lining support Includes Bifidobacterium infantis for digestive comfort Includes Clostridium butyricum to support butyrate production Prebiotic fibers help feed beneficial bacteria Vegetarian delayed-release capsule Third-party tested and made in the USA Get Started WHAT'S INSIDE A smarter gut-support formula for the GLP-1 phase GLP-1 Support combines probiotics and prebiotics in one simple capsule to help support the digestive changes that can happen during a GLP-1 routine

Because both can slow gastric emptying, food may remain in the stomach much longer than the standard 8-hour fasting window