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Collectively, NAD + exerts its effects not through traditional receptor binding but through its indispensable role as a co-substrate and regulator of these enzymatic systems, which sense and respond to fluctuations in NAD + levels to coordinate cellular metabolism, survival, DNA repair, signaling, and cell fate decisions 1-4

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When your body sustains injury or when chronic inflammation damages internal tissues, accelerated, focused healing is paramount

J Physiol (Paris) 1999