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Rett syndrome, caused by MECP2 gene mutations, disrupts GABAergic interneuron development, lowering GABA concentrations in the hippocampus and prefrontal cortex, leading to developmental regression, such as loss of language and motor skills, and stereotypic hand movements like hand-wringing (77)

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Pet/mr imaging of a lung metastasis model of clear cell renal cell carcinoma with (2s,4r)-4-[ 18 F]Fluoroglutamine