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Additionally, ROS/RNS generated by pyocyanin modifies FOXA2 post-translationally, further contributing to mucus overproduction ( P

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Upon sensing environmental stress or cellular damage, the absent in melanoma 2 inflammasome (AIM2) and NLR family pyrin domain-containing 3 (NLRP3) inflammasome assemble and recruit the inflammasome adapter protein apoptosis-associated speck-like protein containing CARD, leading to the activation of pro-inflammatory caspases [137]

52,53,54,55,56 Overall, adiponectin has a main role in the control of inflammation and antioxidant processes, especially in obesity-related asthma

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