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GLP-1 and GLP-2 are real proglucagon-derived gut peptides with established biological roles

Food and Drug Administration (FDA) and the European Medicines Agency (EMA) will determine when these treatments can be prescribed to patients

Youre pregnant, planning to become pregnant, or breastfeeding

58,59 Overall, the future research direction of GLP-1RAs involves making them more similar to those in the human body, extending their duration of action, and creating oral formulations for easier administration

Gallbladder disease In patients with established gallbladder disease, the relative risks and benefits of a cholecystectomy or preventive treatment with ursodeoxycholic acid before starting GLP-1 receptor agonist therapy should be thoroughly discussed

Overall the risks are small and for many probably dont outweigh the benefits