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The highest concentrations tested for sertraline, thioridazine, astemizole and clomipramine were associated with viability 60% relative to controls and resulted in lower SQSTM1/p62 abundance compared to their maximal responses

In fact, oxidative stress is increasingly recognised as a contributing factor in stone formation, and glutathione's antioxidant function may have a modest protective effect on renal epithelial cells that are vulnerable to crystal adhesion

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In some embodiments, a low viscosity otic formulation or device described herein provides an apparent viscosity of from about 500 cP to about 10,000 cP

J Equine Vet Sci 2013;33:3478