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The mechanism is central - GLP-1 receptor agonists act on appetite-regulating centers in the brain in addition to slowing gastric emptying
PMID: 16278749
If the BALANCE Model launches in some future year with at least 80% participation, Part D plans could drop out of the model before the final year (originally 2031), which could interrupt treatment, or require frequent plan changes for Medicare Part D enrollees to maintain access
Insurance coverage for GLP-1 medications varies widely by plan, and some GLP-1 medications may not be covered by insurance
Agriculture is also likely to be impacted, both through the decreased demand for food overall and the shift to increased preferences for protein (Roe, 2025
We conducted a thorough review of the existing evidence to support people living with type 2 diabetes and their health-care providers in the selection of glucose-lowering agents
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