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6.5 mM (Asn 247/Asn 395, **P = 0.0022)

Rather than directly supplying NAD+ precursors (like NMN or NR), it works by blocking an enzyme that consumes nicotinamide, theoretically preserving the substrate pool for endogenous NAD+ production

For example, critics of the 2013 Brewer study argue that the control group was explicitly selected because they had no history of mold exposure, which statistically guarantees a positive relationship and introduces selection bias

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