Because both estrogen and GLP-1 are known to act on receptors in the hypothalamus, research suggests that both may work through converging signaling pathways to regulate lipid and glucose metabolism
GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate beta-cell mitochondrial remodelling and function
Low-level lysosomal membrane permeabilization for limited release and sublethal functions of cathepsin proteases in the cytosol and nucleus
Screening of 49 probiotic strains revealed that two probiotics, Saccharomyces boulardii and Lactococcus lactis , increased recruitment of Parkin to mitochondria, accumulation of phosphoubiquitin, and degradation of mitofusins [139]
Gamma-tocopherol, a major form of vitamin E in diets: insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management
Only about a quarter of people with opioid addiction are taking effective medicines to prevent overdoses, and half discontinue treatment within six months, researchers said