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What comorbidities

At the highest dose of 12 mg retatrutide, the average weight loss after 48 weeks was 24.2% with reduction up to 30% from the baseline weight in 25% of participants

Inventing liraglutide, a glucagon-like peptide-1 analogue, for the treatment of diabetes and obesity

2024 research from Nutrition & Diabetes outlined the economic impact of obesity related to excess medical costs, absenteeism, disability payments and workers compensation payments

Glucagon, secreted by alpha cells in the pancreas, is an important hormone that promotes the release of glucose from the liver into the bloodstream (Robertson, 2023)

Eli Lilly recently reported that its daily oral GLP-1 candidate (orforglipron) achieved significant weight loss (~1215% over 36 weeks) with side effects similar to injectable GLP-1s