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For patients with significant joint damage, tirzepatide is often most useful as a foundation alongside regenerative treatments like PRP or a broader pain management plan improving the terrain so targeted treatments work better

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Mandate inclusion of LMIC patients in international clinical trials to ensure therapeutic relevance and accessibility across populations

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Although prophylactic antibiotic therapy can provide temporary protection, it is counterbalanced by the risk of accelerating antimicrobial resistance

2 Based on preclinical data, retatrutide has shown a promising approach to addressing these unmet clinical needs