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The approval was granted based on demonstrated improvements in MASH and fibrosis, and a confirmatory study is currently underway

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However, these side effects are often intermittent, mild, and short-lived, Fishman says

What began as treatments for diabetes and obesity has rapidly expanded into prevention of cardiovascular disease, slowing kidney decline, tackling liver disease, and even tentative explorations into neurodegeneration

The potential for increased fertility is a side effect

The condition is often associated with significant negative health consequences such as neurocognitive impairment, excessive daytime sleepiness, hypertension, cardiovascular disease, and other metabolic disorders