10.4158/ep161365.Gl [DOI] [PubMed] [Google Scholar] 2
Experimental studies have shown that PCs offer protective effects against diabetic nephropathy, neuropathy, and cardiovascular diseases
In patients with poor glycaemic control, improved glycaemic control (assessed by HbA1C) was associated to an increased skeletal mass index and gait speed [17, 18]
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later, HbA1c was included in the diagnostic criteria for expanded screening
Moreover, because the TMD is less accessible than the extracellular region, this approach may facilitate the design of peptide ligands with moderate binding to better distinguish between target cells and nontarget cells