However, NTAPP did not induce a statistically significant elongation of hHFs in the ex vivo organ culture model (data not shown), and Ki-67+ keratinocytes in matrix were not significantly increased in NTAPP-exposed hHFs (Supplementary Figure 6)
This decline correlates with many aging markers: Body composition changes: Increasing fat mass, particularly visceral fat, with decreasing lean muscle mass
Schietzel et al., 2019
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