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Tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) due to thyroid C-cell tumor findings in rodent studies

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BPC-157 and TB-500 also reduce inflammation in animal studies, but as a secondary effect of their tissue-repair pathways, not as a primary mechanism

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