Ive been on those since like 2018
For a full breakdown of what to anticipate by dose, see retatrutide side effects: what to expect
305 , E376E387 (2013)
The main benefits of GLP-1 therapy include: Enhanced insulin secretion in response to meals Reduced glucagon release, preventing high blood sugar levels Slowed gastric emptying, leading to prolonged satiety Decreased appetite, which may help with weight loss Currently available GLP-1 receptor agonists include drugs like liraglutide (Victoza), semaglutide (Ozempic, Wegovy), exenatide (Byetta), and dulaglutide (Trulicity)
Thus, A 2A R antagonists block the effects of adenosine and facilitate D 2 R agonist effects on lowering cAMP levels and then dampens PKA activity, which may result in neuroprotective effects
Once the patent expires, other companies can produce generic versions, which drives down the cost