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These effects are modest, but they are at least documented

doi: 10.1016/j.redox.2021.101901 48 BasuA

Diabetes and high blood pressure, for example, increase the risk of damage to small blood vessels, including those supplying the optic nerve

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Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on February 16th, 2026

Whats more, the visceral fat around your organs releases signals that raise low-grade inflammation and make insulin less effective, setting up a vicious cycle: Less muscle and more visceral fat leads to more inflammation, worse insulin sensitivity, and easier fat gain around the middle