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J Transl Med 24 , 237 (2026)

Zhong et al., 2002

The short answer is: Yes, its a safe and common practice

Their bioactivity and chemical stability enable them to remain persistent in the environment, where they can bioaccumulate and exert toxicological effects on aquatic and terrestrial organisms, as well as humans [32, 61, 70]

Methylene blue methemoglobinemia treatment acts as a reducing agent, converting methemoglobin back to hemoglobin to restore oxygen transport in the blood