The consequence of both modifications is to lower glutathione synthesis and cellular levels, thus making this essential co-factor less available to exert its multiple biological functions
Cancer 52 , 2330 (2021)
And what that typically means when you have a lot of drugs in a class, the route to approval becomes more difficult, the hurdles get a little harder
Miyoshi T, Nakamura K, Yoshida M, Miura D, Oe H, Akagi S, Sugiyama H, Akazawa K, Yonezawa T, Wada J, Ito H
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