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The first goal of these trials was to prove GLP-1 receptor agonists cardiovascular safety, and majority of CVOTs were designed as non-inferiority trials

Wegovy (injectable semaglutide), Saxenda (liraglutide), and Zepbound (tirzepatide) are some of the popular ones

The calorie guide for semaglutide and calorie guide for tirzepatide provide nutrition targets

Rheumatol Int (2017) 37(1):2942

Candidates for GLP-1 medications must undergo a medical evaluation to assess their health status, medical history, and any potential risks or contraindications