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Moreover, increasing evidence suggests that Nrf2 is involved in the occurrence of ferroptosis and can regulate the expression of antioxidant response elements such as GPx4 [281]

Weight management is a long game

demonstrated that mice given oral glutathione showed increased concentrations in kidney, heart, lung, brain, and small intestine within one hour

caution and monitoring are advised

For more than 50 years metformin has been used to control hyperglycaemia in patients with type 2 diabetes, and it is currently recommended as the first-line drug treatment along with lifestyle modification [1]

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