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Bilodeau PA, Coyne ES, Wing SS (2016) The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation

The Science SLU-PP-332 is a novel small molecule agonist of estrogen-related receptor alpha (ERR), a key regulator of cellular energy metabolism and mitochondrial function

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The release of Cytc from the damaged mitochondria causes oligomerization of Apaf-1, activation of caspase-9, and subsequent conversion of procaspase 3 to caspase-3, which is responsible for many of the apparent symptoms of apoptosis (133,134)

Moreover, in some conditions there may be an ectopic production of thyroid hormones, leading to increased thyroid hormones and a compensatory decrease of TSH, Table 1 (Oo KM n.d

Blood 110(11):220a, 2007