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If you dont have a vitamin B12 deficiency to begin with or you dont first address the underlying causes of a deficiency, high doses of vitamin B12 will not work to improve your quality of life

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For example, valproic acid treatment can exhaust carnitine in the body through various mechanisms, like increased removal via urine, reduced absorption in the kidneys, and decreased natural production

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While the renal biochemistry values were significantly increased at the end of the study, this finding would be expected for any CHF patient after chronic diuretic administration

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