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Current Pharmaceutical Design, 24(18), 1972-1989

Document whether the injection was intramuscular (IM) or subcutaneous (SQ/SC)

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The main concern is stacked GI side effects - both compounds slow digestion through different pathways, so combining them can amplify nausea, vomiting, and constipation

To improve DE differentiation, the researchers incorporated PI3K inhibitor LY294002 (Ly) or CDK4/6 inhibitor PD into the small-molecule cocktails