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It should be noted that while the HIF pathway can induce antioxidant genes like SOD2 to maintain adaptive balance under acute hypoxia, this protective effect in chronic diseases like cancer may conversely aid malignant cells in resisting apoptosis, constituting another dimension of intervention complexity [501]

Cell 2014;156:31731

Hair Growth TB500s potential impact on hair growth adds another intriguing dimension to its versatility

Even though developing a vaccine against GPNMB positive cells seems to be beneficial, the challenge remains to only deplete cells with the highest expression of the protein but not the cells expressing it at a physiological level 63

R.BuontempoF.LucangioliS

Cuadrado et al., 2020