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George Kramer, is researching the viability of a balloon device, called the Tucker valve (left) , which is inserted through either the mitral or the tricuspid valve in order to block regurgitation of blood through the valve back into the atrium

it helps regulate blood sugar, slows gastric emptying, and influences appetite, leading to significant, sometimes dramatic shifts in metabolic health

Female participants were reasonably represented in the completed trials, but no assessment of biological sex differences in drug efficacy and safety profiles was made (196)

Most people tolerate tirzepatide well, with common side effects being mild nausea and gastrointestinal changes that typically resolve within weeks

doi: 10.1210/jc.2002-021518 14 ValassiESantosAYanevaMTothMStrasburgerCJChansonPet al