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Elderberry leaves with antioxidant and anti-inflammatory properties as a valuable plant material for wound healing

Interestingly, recovery of GOT2 activity by re-expressing an acetylation-mimetic GOT2 in these cells inhibited cellular ROS production and restored mitochondrial NADH levels, cellular ATP production, and cell proliferation (109)

doi:10.3390/antiox10040549 [PubMed] 37

Emerging studies suggest that ferroptosis exacerbates PF progression by promoting macrophage polarization, fibroblast proliferation, and extracellular matrix deposition, ultimately leading to alveolar epithelial cell death and fibrotic tissue remodeling

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Heparanase is a key player in renal fibrosis by regulating TGF- expression and activity