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BPC-157 demonstrates both local and systemic effects, meaning even injections at some distance from the injury site provide benefit, though local administration may optimize outcomes

Adjusting the dosage under medical supervision is recommended

The caudal approach may be less effective but is considered safer and easier to perform

High Absorption Rate Almost the entire injected dose becomes available to the body, making it highly reliable for severe cases

1 Mecobalamin 50 mg or placebo was administered intramuscularly twice weekly for 16 weeks to 130 ALS patients who had suffered from ALS for less than one year, were classified as definite, probable, or probable-laboratory supported according to the Updated Awaji Criteria, had an ALS severity rating of grade 1 or 2, had a decrease of 1 or 2 points in the total score on the Revised ALS Functional Rating Scale-Revised (ALSFRS-R) 12 weeks prior to administration, and had a forced vital capacity (%FVC) of more than 60%

Injecting B12 into acupuncture points can help stimulate nerve regeneration and circulation