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Important contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, and pregnancy

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Some patients also report reduced food intake leading to lower core body temperature throughout the day

Knerr PJ, Mowery SA, Douros JD, Premdjee B, Hjollund KR, He Y, Kruse Hansen AM, Olsen AK, Perez-Tilve D, DiMarchi RD, et al