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Dysbiosis, particularly a reduction in beneficial microbes, shifts tryptophan metabolism toward the kynurenine pathway, leading to the production of neurotoxic metabolites (e.g., quinolinic acid) associated with neuroinflammation and depressive symptoms [5, 8, 22]

In a randomized, controlled, double-blind trial, the addition of 200 mg CoQ10 daily in people taking statins and omega-3 fatty acids improved a range of cardiovascular risk factors

Schneider BE, Mun EC

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In some research protocols, the effect is so minimal as to be barely noticeable

Raw scores ranging from 8 to 40 are converted to a T -score with a mean of 50 (Yu et al., 2012)