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While it was once thought to primarily affect insulin secretion, researchers have discovered that GIP plays crucial roles in appetite regulation, fat metabolism, and energy expenditure

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Ethics declarations Conflict of interest The authors have no conflict of interest to disclose

Well for a start, many of the drugs described above are seriously heavyweight therapeutics, with a range of complex effects on the body

Early concerns that GLP-1 medications might worsen kidney function have not been supported by long term data

Improves insulin sensitivity and glucose metabolism