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Effects of GLP-1R activation in the heart The observation that GLP-1 decreases contractility in primary culture of adult rat cardiomyocytes, despite increasing cAMP levels, [38] has also been reported in isolated rat hearts [45]

Currently, 40% to 50% of liver recipients are infected with HCV, whereas the proportion of cardiac, lung, and kidney transplant recipients with HCV infection is lower

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Due to these combined effects, GLP-1 drugs are effective not only in controlling blood sugar levels but also in managing obesity, making them a dual-benefit therapeutic option

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