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10.1016/j.ejmech.2015.04.040 56

These often diminish over time as the body adjusts

This study compared thousands of patients treated in real clinics, which is powerful, but it wasnt a randomized trialso results dont prove cause-and-effect for every person

Estos efectos son generalmente ms pronunciados durante las primeras semanas de tratamiento o despus de aumentos de dosis, y tienden a ser dosis-dependientes

Caffeine can sometimes speed up digestion, which might reduce the time the supplement has to absorb