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To view or add a comment, sign in RBM20 truncating variants were associated with reduced lifetime penetrance and milder disease in #DilatedCardiomyopathy compared to pathogenic RBM20 or titin variants, suggesting a low-effect role in arrhythmogenic cardiomyopathy

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For example, cigarette smoke speeds up phase I, which can lead to a build-up of highly toxic substances waiting to be removed via phase II

10.1016/j.ijbiomac.2018.06.104 25 GaoQ.WangY.WangX.FuS.ZhangX.WangR.-T.et al (2019)

Although external stimuli induce ChaC1/ChaC2 gene and GGT expression (15,174,175), the specific regulatory mechanisms governing these inductions remain unclear