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They can play the role of GLP-1

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The more pronounced decline in hip BMD, as compared to the relative preservation of lumbar spine BMD, is likely due to the predominance of mechanically responsive cortical bone in the hip, whereas the lumbar spine is composed largely of metabolically active trabecular bone

Casanueva FF, Moreno B, Rodriguez-Azeredo R, Massien C, Conthe P, Formiguera X, et al