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Supplementary information Supplementary Data 1 (download ZIP Original as well as cropped pictures of islet histology shown in Extended Data Fig
GLP-1s for Chronic Kidney Disease GLP-1s for Advanced Liver Disease In August 2025, the FDA approved Wegovy (semaglutide) to treat adults with a type of liver disease called metabolic-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), when used alongside diet and exercise
(1) By binding to GLP-1 receptors, Semaglutide: Enhances insulin secretion Suppresses glucagon release (which reduces blood sugar levels) Delays gastric emptying Promotes satiety These combined actions have been shown to help regulate blood sugar levels and reduce appetite
Limit the consumption of salty and sugary foods, alcohol, and caffeine
Maile LA, Badley-Clarke J, Clemmons DR
