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Bravo Gonzalez-Blas, C et al

and, most importantly, we see the same senitization to 5FU with other CI inhibitors, such as IACS-010759, phenformin and carboxyamidotriazole, as we do with metformin

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doi:10.1016/j.tibs.2006.11.006 Guse AH

Hormonal fluctuations, particularly in females, can affect ligament laxity and susceptibility to injury, as variations in estrogen levels have been linked to changes in the mechanical properties of the ACL