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Drug Interaction Profile and Absorption Considerations Semaglutide slows gastric emptying, which theoretically affects how quickly oral medications reach peak absorption

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Tirzepatide, by affecting GLP-1 receptors in the brains hypothalamus (a region that influences both appetite and certain mood functions), can contribute to a feeling of less anxiety surrounding food, promoting a more balanced perspective on eating

The problem: natural GLP-1 lasts only a couple of minutes before enzymes break it down