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To improve the selectivity, in this work, we design and synthesize a malononitrile-functionalized TPE derivative, TPE-DCV, which can undergo addition reaction with thiol group to the alkene bond, leading to the change in its fluorescence in the system (Figure 1)

Engineered histidine-rich peptides enhance endosomal escape for antibody-targeted intracellular delivery of functional proteins

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GTT experiments were performed twice with five or six mice per test article

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The article lists four baseline factors: estimated glomerular filtration rate, hydration status and daily fluid intake, an electrolyte panel covering sodium, potassium and magnesium, and body composition including lean muscle mass