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Under physiological conditions, microglia are essential for maintaining neuronal energy, with the expression of Trem2 playing a crucial role in microglia-mediated synaptic refinement
His oxygen saturation was critically low at 46% on room air
The company said no plateau was observed after patients transitioned to monthly dosing, which suggests that continued weight loss is expected as the study continues through week 64
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However, like all medications, it requires careful consideration of potential side effects, including muscle pain
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