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For instance, two recent studies have identified GPT2-mediated coupling of pyruvate production to glutamine catabolism in two different tissue types: PIK3CA-mutated colorectal cancer cells (Hao et al, 2016), and Ras- and p53-transformed YMAC cells (Smith et al, 2016)

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Witzdam, T

Adv Exp Med Biol (2021) 1307:17192

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Scroll right for full table The complete discussion is available here this part begins at 2:50 NAD+ NAD+ is one of the compounds Gary Brecka talks about frequently when discussing cellular energy and aging