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Researchers use LC-MS to verify: .Molecular weight .Peptide identity .Structural integrity .Manufacturing accuracy Combining HPLC with LC-MS provides a comprehensive assessment of peptide quality

The practical takeaway: The direction is changing, but the change is not yet complete

It is of higher quality than the artificially produced cyanocobalamin

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Chemical Engineering Journal, 346: 298306 Yu Y, Lee C, Kim J, Hwang S (2005)